Novel synthesis of Pyrimido[4,5- e] [1,3,4] thiadiazines

Journal of Chemical Reactivity and Synthesis

مقاله 1، دوره 4، شماره 2، آذر 2014، صفحه 1-7   

نوع مقاله: Research Article

نویسنده

Abdolhassan Doulah^*

Department of Nursing, Faculty of Nursing and Midwifery, Islamic Azad University, Ahvaz Branch, Ahvaz, Iran

چکیده

Treatment of 1-(5-bromo-2-chloro-6-methylpyrimidin-4-yl)-1-methylhydrazine with dimethylthiocarbamoylchloride gave 7-chloro-N,N,1,5-tetramethyl-1H-pyrimido[4,5-e][1,3,4]thiadiazin-3-amine in basic acetonitrile. The latter compounds were reacted with secondary amines in boiling ethanol to afford the related 7-amino derivatives.

کلیدواژه‌ها

1-(5-bromo-2-chloro-6-methylpyrimidin-4-yl)-1-methylhydrazine؛ dimethylthiocarbamoylchloride؛ pyrimidothiadiazine؛ 15- lipoxygenase

مراجع

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