One-pot Synthesis of Polysubstituted Dihydro-2oxypyrroles Catalyzed by Vanadium (V) oxide

Journal of Applied Chemical Research

مقاله 10، دوره 11، شماره 1، فروردین 2017، صفحه 115-123   

نوع مقاله: Research Paper

نویسندگان

Farzaneh Mohamadpour؛ Malek Taher Maghsoodlou^* ؛ Reza Heydari؛ Mojtaba Lashkari

چکیده

A mild and efficient synthesis of polysubstituted dihydro-2-oxypyrroles has been developed for the one-pot, four-component domino condensation of dialkyl acetylenedicarboxylate, formaldehyde and aromatic amines using Vanadium (V) oxide as the catalyst at ambient temperature. The use of Vanadium (V) oxide makes this process simple, more convenient, and environmentally friendly.

کلیدواژه‌ها

Vanadium (V) oxide؛ Dihydro-2-oxypyrrole derivatives؛ Multi-component reactions؛ Eco-Friendly