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Three-component Process for the Synthesis of Some Thiophene Derivatives Using Water as a Green Media | ||
Journal of Applied Chemical Research | ||
مقاله 1، دوره 11، شماره 2، مرداد 2017، صفحه 8-13 اصل مقاله (173.45 K) | ||
نویسنده | ||
Ali Varasteh Moradi* | ||
Department of Chemistry, Gorgan Branch, Islamic Azad University, Gorgan, Iran. | ||
چکیده | ||
A convenient and efficient three-component reaction to a one-pot synthesis of thiophene derivatives from activated acetylenic compounds and ethyl 2chloroacetoacetate in the presence of tetramethyl thiourea in water lead to the formation of thiophenes in good yields. | ||
کلیدواژهها | ||
One-pot reactions؛ Tetramethyl thiourea؛ Ethyl 2-chloroaceto acetate | ||
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