A Simple, Practical and Efficient Method for the Synthesis of New Disubstituted 1,3,4-oxadiazoles

Journal of Applied Chemical Research

مقاله 7، دوره 11، شماره 2، مرداد 2017، صفحه 76-85   

نویسندگان

Ali Ramazani^{* 1}؛ Delnia Zamanesazi؛ Yavar Ahmadi²؛ Pegah Azimzadeh Asiabi¹؛ Ali Souldozi³؛ Sang Woo Joo^*

¹Department of Chemistry, University of Zanjan, Zanjan, Iran

²North West Reseach Complex, Nuclear Science and Technology Research Institute, Bonab, Iran

³Department of Chemistry, Urmia Branch, Islamic Azad University, Urmia, Iran

چکیده

Reactions of  N-isocyaniminotriphenylphosphorane with α- chloroketones in the presence of
aromatic carboxylic acids proceed smoothly at room temperature and in neutral conditions to
afford new disubstituted 1,3,4-oxadiazole derivatives in high yields.

کلیدواژه‌ها

N-isocyaniminotriphenylphosphorane؛ aromatic carboxylic acid؛ α- chloroketone؛ 1؛ 3؛ 4-oxadiazole؛ aza-Wittig reaction