Reaction of benzoylpyruvate with a mixture of aromatic aldehydes and 5-amino-1,3,4-thiadizole-2-thiol

Journal of Chemical Reactivity and Synthesis

مقاله 6، دوره 7، شماره 1، خرداد 2017، صفحه 60-70   

نوع مقاله: Research Article

نویسندگان

Neda Tavakkoli^* ؛ Hassan Kabirifard

Department of Chemistry, North Tehran Branch, Islamic Azad University, Tehran, Iran

چکیده

Reactions of benzoylpyruvate with a mixture of aromatic aldehydes and 5-amino-1,3,4-thiadizole-2-thiol in a 1:1:1 molar ratio, afforded 5-(5-aryl-4-benzoyl-3-hydroxy-2-oxo-2,5-dihydro-1H-pyrrol-1-yl)-1,3,4-thiadizole-2-thiols (3a-c). The structure of the resulted products was confirmed by determination of the melting point and spectrophotometric techniques such as IR and 1H-NMR spectroscopy.

کلیدواژه‌ها

Benzoylpyruvate؛ Aromatic aldehydes؛ 5-amino-1,3,4-thiadizole-2-thiol؛ Multi-component reactions (MCRs)