Isolation and identification of growth promoting endophytes from Artemisia annua L. and its effects on artemisinin content

Trends in Phytochemical Research

مقاله 4، دوره 1، شماره 4، اسفند 2017، صفحه 207-214   

نوع مقاله: Original Article

نویسندگان

Mir Abid Hussain^{1، 2}؛ Vidushi Mahajan^{1، 2}؛ Irshad Ahmad Rather¹؛ Praveen Awasthi¹؛ Rekha Chouhan¹؛ Prabhu Dutt¹؛ Yash Pal Sharma³؛ Yashbir S. Bedi^{1، 2}؛ Sumit G. Gandhi^{* 1، 2}

¹Indian Institute of Integrative Medicine (CSIR-IIIM), Council of Scientific and Industrial Research, Canal Road, Jammu-180001, India

²Academy of Scientific and Innovative Research, Anusandhan Bhawan, 2 Rafi Marg, New Delhi-110 001, India

³Post Graduate Department of Botany, University of Jammu, Jammu and Kashmir, India

چکیده

Artemisinin, a sesquiterpene lactone, is a well-known antimalarial drug isolated from Artemisia annua L. (Asteraceae). Semi-synthetic derivatives of artemisinin like arteether, artemether, artesunate, etc. have also been explored for antimalarial as well as other pharmacological activities. Endophytes are microorganisms which reside inside the living tissues of host plants and can form symbiotic, parasitic or commensalistic relationship depending on the climatic conditions and host genotype. In this study, endophytic fungi were isolated from the leaves of A. annua and were identified using the conventional as well as molecular taxonomic methods. Endophytes were identified as: Colletotrichum gloeosporioides, Cochliobolus lunatus, Curvularia pallescens and Acremonium persicum. Growth promoting activity of endophytes has been reported earlier. After treating potted plants of A. annua with elicitor extracts prepared from these endophytic fungi, we observed an increase in the plant biomass as well as artemisinin content.

کلیدواژه‌ها

Acremonium persicum؛ Cochliobolus lunatus؛ Colletotrichum gloeosporioides؛ Curvularia pallescens؛ Elicitor

سایر فایل های مرتبط با مقاله

Supplementary Table S1.docx

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