Synthesis of new trisubtitued imdidazole compounds in solvent free condition

Journal of Chemical Reactivity and Synthesis

مقاله 4، دوره 7، شماره 4، اسفند 2017، صفحه 29-37   

نوع مقاله: Research Article

نویسنده

Omid Baravaye^*

Departmentof Chemistry, School of Sciences, Islamic Azad University, Ahvaz Branch, Ahvaz, 6134968875, Iran

چکیده

Treatment of 7-chloro-1-phenylpyrimido[4,5-e][1,3,4]thiadiazines with hydrazine in boiling ethanol gave corresponding7-hydrazinyl derivatives. Diazotization of the latter compounds acheived a mixture of 5H-tetrazolo[1',5':1,2]pyrimido[4,5-e][1,3,4]thiadiazine and 9H-tetrazolo[5',1':2,3]pyrimido[4,5-e][1,3,4]thiadiazines. Ratio of these two group of products determined by ¹HNMR studies and no significant preference was observed for their formation. Efforts for separation of the products were unsuccessful and its reason is discussed.

کلیدواژه‌ها

trisubstitution؛ imidazole؛ solvent free