Synthesis of 5-amino-1-aryl-4-cyanoimidazoles from formamidines under solvent-free condition

Iranian Journal of Catalysis

مقاله 2، دوره 3، شماره 1، خرداد 2013، صفحه 9-13   

نویسندگان

Asieh Yahyazadeh؛ Farhad Shirini^* ؛ Fatamah Tavakoli

Department of Chemistry, University of Guilan, P.O. Box 41335-1914, Rasht, I.R. Iran.

چکیده

The aryl-(Z)-N-[2-amino-1,2-dicyanovinyl]formamidine 2 cyclize in solvent-free conditions and in the presence of a base to give a 5-amino-1-aryl-4-cyanoimidazoles 3. Silica sulfuric acid as an efficient and reusable heterogeneous catalyst has been used for the preparation of amidines 2 from formimidate 1 through reaction with aromatic amines at room temperature and in good to excellent yields. All these derivatives were fully characterized by spectroscopic data.

کلیدواژه‌ها

Silica sulfuric acid؛ Heterogeneous catalyst؛ Imidate؛ Amidine؛ Aiaminomaleonitrile؛ Cyanoimidazole

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