Antibacterial activity of different extracts from the aerial parts and roots of Stachys lavandulifolia Vahl harvested at two stages of growth

Journal of Medicinal Herbs, "J. Med Herb" (Formerly known as Journal of Herbal Drugs or J. Herb Drug)

مقاله 2، دوره 5، شماره 1، تیر 2014، صفحه 7-12   

نوع مقاله: Original article

نویسندگان

Masoud Taheri¹؛ Saman Mahdavi^{* 2}؛ Yousef Mehmannavaz³

¹Department of Botany, Marand Branch, Islamic Azad University, Marand, Iran

²Department of Microbiology, Maragheh Branch, Islamic Azad University, Maragheh, Iran

³Department of Animal Science, Maragheh Branch, Islamic Azad University, Maragheh, Iran

چکیده

Background & Aim: Nowadays, the application of traditional medicine and herbal medicinal plants instead of chemical and synthetic drugs has captured the attention of the researchers. The purpose of this study was to investigate the antimicrobial effects of the aquatic, ethanolic and methanolic (80%) extracts of the aerial and root parts of Stachys lavandulifolia Vahl which were taken from the countryside of Marand (Eastern Azerbaijan, Iran) in two generative and vegetative phases against standard strains of microorganisms. Experimental: Antimicrobial activity of the alcoholic and aquatic extracts from different parts of S. lavandulifolia was investigated against standard strains of Staphylococcus aureus (ATCC 6538), Escherichia coli (ATCC 8739), Pseudomonas aeruginosa (ATCC 9027) through well-plate and micro-dilution methods. Ampicillin as antibacterial agent was used as positive control. Results & Discussion: Results of antimicrobial properties of S. lavandulifolia extracts revealed that the aquatic extract of the plant had no antibacterial effects. While the ethanolic and methanolic (80%) extracts showed the growth inhibition effect against standard strains of examined microorganisms. Their effect against Gram-positive bacteria was higher than Gram-negative bacteria. The antimicrobial activity of the ethanolic extract from the inflorescence of S. lavandulifolia was higher than the alcoholic extract of the roots. Recommended applications/industries: The overall results indicated the ethanolic extract of the inflorescence of Stachys lavandulifolia has the best antimicrobial effects and it can be employed in manufacturing desirable bactericidal agents.

کلیدواژه‌ها

Alcoholic extract؛ Antimicrobial activity؛ Stachys lavandulifolia Vahl

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