Anti-inflammatory activity of leaf extract of Solanum anomalum

Journal of Medicinal Herbs, "J. Med Herb" (Formerly known as Journal of Herbal Drugs or J. Herb Drug)

مقاله 4، دوره 7، شماره 4، فروردین 2017، صفحه 243-249   

نوع مقاله: Original article

نویسندگان

Jude E Okokon^{* 1}؛ Koofreh O. Davies²؛ Louis U. Amazu³؛ Emem E. Umoh¹

¹Department of pharmacology and toxicology, Faculty of pharmacy, University of Uyo, Uyo, Nigeria

²Department of Physiology, Faculty of Basic Medical Sciences, University of Uyo, Uyo, Nigeria

³Department of Pharmacology and Therapeutics, College of Medicine, Evans Enwerem University, Orlu Campus, Imo State

چکیده

Background & Aim: Solanum anomalum Thonn. ex Schumach. (family Solanaceae) is a shrub growing up to 2 metres tall. The edible fruits are gathered from the wild and consumed locally and the leaves are used locally in the treatment of various diseases. Evaluation of anti-inflammatory activity of leaf extract of Solanum anomalum was carried out to ascertain its uses in traditional medicine.
Experimental: The crude leaf extract (70 – 210 mg/kg) of Solanum anomalum was investigated for anti-inflammatory activity using various experimental models; carragenin, egg albumin and xylene induced oedema.
Results: The extract (70 -210 mg/kg) caused a significant (p
Recommended applications/industries: The plant, Breynia nivosa, possesses antiinflammatory property which can be exploited in the treatment of inflammatory diseases.

کلیدواژه‌ها

Solanum anomalum؛ Antiinflammatory؛ Oedema

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