Heterogeneous Catalyst for the One-Pot Synthesis of 1,8-Dioxodecahydroacridine

Journal of Chemical Reactivity and Synthesis

مقاله 7، دوره 8، شماره 4، بهمن 2018، صفحه 48-55   

نوع مقاله: Research Article

نویسندگان

Haleh Sanaeishoar^* ؛ Mitra Serami

Department of Chemistry, Ahvaz Branch, Islamic Azad University, Ahvaz, Iran

چکیده

An efficient and environmental-friendly synthetic route to 1,8-dioxodecahydroacridines derivatives have been developed via multi-component one-pot Hantzsch reaction of various aldehydes and ammonium acetate with 2 equivalents dimedone in the presence of Phosphorus pentoxide supported on aluminaas catalyst under solvent-free conditions. The present approach offersseveral advantages such as short reaction times, easy isolation and purification of product, and safe, non-toxic, recyclable and economic use of catalyst.

کلیدواژه‌ها

Hantzsch؛ Solvent-free؛ One-pot synthesis؛ 1؛ 8-Dioxohexahydroacridine؛ Multicomponent