Solvent Free Synthesis of tetra alkyl- phenyl-1H-pyrimido [4, 5-e][1,3,4]Thiadiazine-3,7-diamines

Journal of Chemical Reactivity and Synthesis

مقاله 6، دوره 9، شماره 1، خرداد 2019، صفحه 67-77   

نوع مقاله: Research Article

نویسنده

mohammad kazem mohammadi

Department of chemistry, Ahvaz Branch, Islamic Azad University, Ahvaz, Iran.

کلیدواژه‌ها

New 1؛ 5-tetra alkyl methyl- phenyl-1H-pyrimido[4؛ 5-e][1؛ 4]thiadiazine-3؛ 7-diamine were synthesized via the cyclocondensation of 2-(5-bromo-2-chloro-6-methylpyrimidin-4-yl)-2-methylhydrazine with phenylthioisothiocyanate and further replacement of chlorine atom on the seven number position of pyrimido[4؛ 5- e][1؛ 3؛ 4]thiadiazin by appropriate secondary amines in simple and efficient methods