Modeling the human retina in patients with glaucoma

Journal of Mechanical Research and Application

دوره 10، شماره 2، آذر 2020، صفحه 26-34   

نویسندگان

afsaneh safdel¹؛ kamran hasani^{* 2}

¹Department of Biomechanics,South Tehran Branch,Islamic Azad University,Tehran,Iran

²Biomedical Engineering Department, Science and Research Branch of Islamic Azad University, Tehran, IRAN.

چکیده

 



Glaucoma is a major risk factor for blindness and causes loss of visual field due to retinal ganglion cell (RGC) destruction. Glaucoma is associated with high blood pressure, cardiovascular disease, and ocular blood flow. Vascular factors play an important role in the development of glaucoma. A number of retinal vascular parameters are measured for use in software from retinal imaging. The biomechanical model of the disease reveals that mechanical stress induced by IOP impairs the function of retinal ganglion cells. Due to the difficulty of direct retinal biomechanical measurement in determining ocular biomechanics, the current study uses modeling with significant limitations to make it easier to examine.The purpose of this article is to stimulate the human retina in patients with glaucoma. In this research, the applied stresses on the inner surfaces of the retina and its effects on the inner parts are studied. Intraocular pressure (IOP) is considered to be higher than 20 mm Hg. With this model, we can study stresses and strains in different and desired conditions. The way of applying load is compressive load on the retina

کلیدواژه‌ها

Glaucoma؛ Intraocular pressure؛ Retina؛ Finite element method؛ Stress