Multicomponent Reactions Synthesis of Triaryl-1H Imidazoles Using Reductive-oxidative Reactions by MnO2-FeSO4 as a Catalyst

Journal of Chemical Health Risks

دوره 11، شماره 2، شهریور 2021، صفحه 223-226   

نوع مقاله: Original Article

شناسه دیجیتال (DOI): 10.22034/jchr.2021.682034

نویسندگان

Ali A.Raheem^* ؛ Ali T.Saleh

University of Misan, college of Sciences, Chemistry department, Misan,62001, Iraq

چکیده

The study's chief purpose is to investigate multicomponent reactions synthesis of triaryl-1h imidazoles using reductive-oxidative reactions by MnO₂ - FeSO₄ as a catalyst.Some novel substituted imidazoles have been synthesized using MCRs, one-pot synthesis, and MnO₂/FeSO₄ as a catalyst; the method involves the reaction of benzil, aromatic aldehyde, and ammonium acetate in the presence of MnO₂/FeSO₄ as a reductive-oxidative catalyst under mild conditions. the obtained compounds were nontoxic, excellent yields, and environmentally friendly. The compounds were elucidated  using IR and ¹H-NMR spectra. To satisfy the aim of the study, Reactions have been performed simply by mixing 1,2-diketone with an aldehyde and ammonium acetate in the presence of the catalytic reagent of MnO₂/FeSO₄. The mixture was prepared by ground them together in a mortar with a pestle at room temperature for several minutes; after that, they purified by column chromatography, 2,4,5-triaryl substituted imidazole derivatives were obtained in excellent yields.

کلیدواژه‌ها

Multicomponent Reactions؛ Triaryl-1H Imidazoles؛ Reductive-oxidative؛ Catalyst؛ MnO2-FeSO4

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