نقش جنسیت در سطح فاکتور رشد اندوتلیال عروقی سرم و پاسخ آن به فعالیت ورزشی

فصلنامه علوم ورزش

مقاله 2، دوره 12، شماره 40، بهمن 1399، صفحه 31-56   

نوع مقاله: علمی پژوهشی

نویسندگان

مهدی یادگاری¹؛ علی اصغر رواسی^{* 2}؛ عباسعلی گائینی²؛ هاجر پاکمنش³؛ پریناز مصدق³

¹دکتری تخصصی، گروه فیزیولوژی ورزشی دانشکده تربیت بدنی و علوم ورزشی، دانشگاه مازندران، بابلسر، ایران

²استاد، دکترای تخصصی فیزیولوژی ورزشی، گروه فیزیولوژی ورزشی، دانشکده تربیت بدنی و علوم ورزشی ، دانشگاه تهران، تهران، ایران

³کارشناس ارشد، گروه فیزیولوژی ورزشی دانشکده تربیت بدنی و علوم ورزشی، دانشگاه تهران، تهران، ایران

چکیده

تفاوت های جنسیتی زیادی در شاخص های ظرفیت عملکردی و پاسخ به استرس ورزشی وجود دارد. فاکتور رشد آندوتلیال عروقی (VEGF) واسطه مهم در فرایند آنژیوژنز و از عوامل توسعه توان هوازی به شمار می رود. هدف پژوهش حاضر بررسی نقش جنسیت در سطح VEGF سرم و پاسخ آن به فعالیت ورزشی بود.  11 مرد و 11 زن (میانگین سنی80/1±80/23 و64/1±63/22 سال) غیر ورزشکار انتخاب و به اجرای یک جلسه فعالیت هوازی پیشرونده پرداخت اند. نمونه های سرمی قبل، بلافاصله و 2 ساعت بعد از اجرا جمع آوری و سطوح VEGF سرمی با کیت الایزا اندازه گیری شد. بررسی داده ها با استفاده از آزمون های آماری تحلیل واریانس با اندازه گیری های تکراری و t مستقل انجام شد. یافته ها نشان داد سطح VEGF سرمی زنان در حالت استراحت به طور معناداری از مردان بیشتر بود (002/0P= )، در حالی که این اختلاف بلافاصله (052/0P=) و دو ساعت بعد از فعالیت ورزشی (077/0P=) مشاهده نشد. بر اساس یافته های پژوهش حاضر به نظر می رسد در حالت استراحتی، زنان نسبت به مردان دارای سطح بالاتری از فاکتور رشدی اندوتلیال عروقی هستند اما در پاسخ به استرس ورزشی این مردان هستند که افزایش بیشتری در VEGF سرمی تجربه می کنند.

کلیدواژه‌ها

آنژیوژنز؛ جنسیت؛ فاکتور رشدی؛ فعالیت هوازی؛ توان هوازی

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