Evaluation of plasma changes of hepcidin, total sialic acid and sphingosine 1 phosphate in buffaloes with hepatic hydatidosis

Journal of Basic and Clinical Veterinary Medicine

دوره 2، شماره 1، 2021، صفحه 32-37   

نوع مقاله: Original Article

شناسه دیجیتال (DOI): 10.30495/jbcvm.2021.1930308.1008

نویسندگان

Omid Mohammadpour^{* 1}؛ Sohrab Rasouli²؛ Kaveh Azimzadeh³؛ Maryam Salarpour¹؛ Ariyan Narouie¹

¹Department of Clinical Sciences, Faculty of Veterinary Medicine, Shahid Bahonar University of Kerman, Kerman, Iran

²Department of pathobiology, Veterinary Faculty, Urmia Branch, Islamic Azad University, Urmia, Iran

³Department of Clinical Sciences, Veterinary Faculty, Urmia Branch, Islamic Azad University, Urmia, Iran

چکیده

The aim of this study was to evaluate plasma changes in hepcidin, total sialic acid (TSA) and sphingosine 1 phosphate (S1P) in buffalos with hydatidosis in the city of Urmia. Hydatidosis is a zoonotic disease that can be very dangerous in humans and even cause death to humans and animals. In this study, the samples were taken from 40 cases of buffalos that suffered from hydatidosis, especially the liver form of the disease, and also 40 buffaloes without hydatidosis all taken from Urmia slaughterhouse. After the separation of plasma samples, the mentioned parameters were measured and analyzed statistically using SPSS version 17. The results indicated a significant increase P<0.05 in all mentioned parameters compared to the healthy group. Based on the above result, it can be noted that hydatidosis causes changes in plasma levels of some parameters. Interpreting some of the parameters would help us come to a better understanding of the complications of the disease. Furthermore, focusing on these parameters along with other plasma parameters would help practitioners in the paraclinical diagnosis of buffalo’s hydatidosis.

کلیدواژه‌ها

Hepcidin؛ Total sialic acid؛ Sphingosine 1 phosphate؛ Buffalo؛ Hydatidosis