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Evaluation of antibacterial properties of chitosan nanoparticles against Esherichi coli isolated from diabetic ulcers | ||
International Journal of Bio-Inorganic Hybrid Nanomaterials | ||
مقاله 2، دوره 10، شماره 1، فروردین 2021، صفحه 11-15 اصل مقاله (901.69 K) | ||
نوع مقاله: Research Paper | ||
چکیده | ||
Nanotechnology is the science to create products with enormous potential to treat diseases. Diabetic ulcers and their infections have affected many people around the world, and many people die each year from infections caused by microorganisms in these ulcers. The aim of this study was to investigate the antibacterial properties of chitosan nanoparticles against Escherichia coli isolated from diabetic wounds. Morphological evaluation and substructure of nanoparticles synthesized by ion gelling method were performed by XRD and TEM. Investigation of the antibacterial properties of chitosan nanoparticles on Esherichia coli by qualitative agar well diffusion test and microdilution was performed to the concentration of 0.064 g/l to 0.256 g/l. The size of chitosan nanoparticles in this study was 100 nm and spherical shape. The sizes of the inhibition zone were different according to the type of bacteria and the concentrations of chitosan, the maximum zone diameter 20 mm in concentration 0.256 g.l being observed. | ||
کلیدواژهها | ||
Antibacterial effect؛ Chitosan nanoparticles؛ Diabetic ulcers؛ Escherichia coli؛ Nanotechnology | ||
آمار تعداد مشاهده مقاله: 207 تعداد دریافت فایل اصل مقاله: 168 |