The genus Micromeria Benth.: An overview on ethnobotany, chemotaxonomy and phytochemistry

Trends in Phytochemical Research

مقاله 1، دوره 6، شماره 3، آذر 2022، صفحه 155-186   

نوع مقاله: Review article

شناسه دیجیتال (DOI): 10.30495/tpr.2022.694114

نویسندگان

Majid Mohammadhosseini^{* 1، 2}؛ Alessandro Venditti³؛ Guido Flamini⁴؛ Satyajit D. Sarker⁵؛ Mohammadreza Kalaee^{6، 7}

¹Department of Chemistry, College of Basic Sciences, Shahrood Branch, Islamic Azad University, Shahrood, Iran

²Nanotechnology Research Center, Islamic Azad University, South Tehran Branch, Tehran, Iran

³Dipartimento di Chimica, Università di Roma “La Sapienza”, Piazzale Aldo Moro 5, 00185 Rome, Italy

⁴Dipartimento di Farmacia, Via Bonanno 6, 56126 Pisa, Italy

⁵Centre for Natural Products Discovery (CNPD), School of Pharmacy and Biomolecular Sciences, John Moores University, James Parsons Building, Byrom Street, Liverpool L3 3AF, United Kingdom

⁶Nanotechnology Research Center, Islamic Azad University, South Tehran Branch, Tehran, Iran

⁷Polymer Engineering Group, Faculty of Engineering, Islamic Azad University, South Tehran Branch, Tehran, Iran

چکیده

The genus Micromeria Benth. from the family Lamiaceae mainly comprises herbaceous plants having several remarkable ethnobotanical, biological and phytochemical applications. This review critically appraises all the information available in the literature, e.g., Scopus, Institute for Scientific Information-Web of Science (ISI-WOS) as well as Medline on various species of this genus covering aspects of biological activity, ethnobotanical, chemical taxonomy and phytochemistry. The phytochemical composition of both essential oils and non-volatile extracts is reported. Their chemotaxonomic implications and ethnomedicinal impacts are also discussed. The pharmacological properties of crude extracts and isolated phytochemicals from Mircomeria spp. observed in several bioactivity tests are also critically reviewed. From phytochemical point of view, the characterization of the organic extracts of different Mircomeria spp. has led to the identification of some valuable natural compounds. Furthermore, the chemical profiles of most of the species are dominated by oxygenated monoterpenes. A wide spectrum of promising biological properties have been attributed to Mircomeria species including antibacterial, antifungal, antioxidant, anticholinesterase, tyrosinase inhibition and antinociceptive activities. Moreover, it has been shown that rosmarinic acid serves as a marker compound in several entities of this genus.

کلیدواژه‌ها

Biological activity؛ Chemotaxonomy؛ Ethnobotany؛ Micromeria؛ Phytochemistry

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