The Genomic Characteristics of SARS-CoV-2 and Emergence of SARS-CoV-2 Variants

International Journal of Molecular and Clinical Microbiology

دوره 13، شماره 1، اردیبهشت 2023، صفحه 1770-1778   

نوع مقاله: Review

شناسه دیجیتال (DOI): 10.22034/ijmcm.2022.1955848.1235

نویسندگان

Gokben OZBEY^{* 1}؛ Alfizah Hanafiah²؛ Yashvanth Shaan Lakshmanappa³؛ Santosh Dhakal⁴؛ Gourapura J Renukaradhya⁵

¹Vocational School of Health Services, Firat University, Elazig, TURKEY

²Department of Medical Microbiology and Immunology, Faculty of Medicine, Universiti Kebangsaan Malaysia, Cheras, Kuala Lumpur, Malaysia

³The Center for Immunology and Infectious Diseases, UC Davis, Davis, California, USA

⁴Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, USA

⁵Department of Animal Sciences, Center for Food Animal Health, Ohio Agricultural Research and Development Center, 1680 Madison Avenue, Wooster, OH 44691, USA

چکیده

The 2019 coronavirus disease (COVID-19) causes global pandemic public health problem in the world. COVID-19 has been defined as a disease that can be transmitted from human to human via respiratory products. Considering COVID-19 pandemic, the publication of articles on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the disease induced by this virus are dramatically increased. This review article aims to gather the knowledge associated to the genomic characteristics and evolution of SARS-CoV-2 strains, thus enlightened us in understanding SARS-CoV-2 pathogenecity that will helps in developing new mitigation strategies. The full genome characterization of SARS-CoV-2 give insight into the virus evolution and adaptation in different populations across the globe. As different variants of strains circulating in various regions and populations, further investigations are necessary to warrant the impact of treatment on different strains.

کلیدواژه‌ها

COVID-19؛ genome characterization؛ pandemic؛ SARS-CoV-2؛ variants