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Khaksar Jalali, Bahareh, Salmani Shik, Somayeh, Karimzadeh Bardee, Latifeh, shahi, sharifeh. (1401). Investigation of the Nonlinear Refractive Index of MCF7 and MCF10A Breast Cell Lines for Optical Diagnosis. نشریه علمی پژوهشی دانشگاه آزاد اسلامی, 2(1), 41-50. doi: 10.30495/ijbbe.2023.699380
Bahareh Khaksar Jalali; Somayeh Salmani Shik; Latifeh Karimzadeh Bardee; sharifeh shahi. "Investigation of the Nonlinear Refractive Index of MCF7 and MCF10A Breast Cell Lines for Optical Diagnosis". نشریه علمی پژوهشی دانشگاه آزاد اسلامی, 2, 1, 1401, 41-50. doi: 10.30495/ijbbe.2023.699380
Khaksar Jalali, Bahareh, Salmani Shik, Somayeh, Karimzadeh Bardee, Latifeh, shahi, sharifeh. (1401). 'Investigation of the Nonlinear Refractive Index of MCF7 and MCF10A Breast Cell Lines for Optical Diagnosis', نشریه علمی پژوهشی دانشگاه آزاد اسلامی, 2(1), pp. 41-50. doi: 10.30495/ijbbe.2023.699380
Khaksar Jalali, Bahareh, Salmani Shik, Somayeh, Karimzadeh Bardee, Latifeh, shahi, sharifeh. Investigation of the Nonlinear Refractive Index of MCF7 and MCF10A Breast Cell Lines for Optical Diagnosis. نشریه علمی پژوهشی دانشگاه آزاد اسلامی, 1401; 2(1): 41-50. doi: 10.30495/ijbbe.2023.699380

Investigation of the Nonlinear Refractive Index of MCF7 and MCF10A Breast Cell Lines for Optical Diagnosis

International Journal of Biophotonics and Biomedical Engineering
دوره 2، شماره 1، دی 2022، صفحه 41-50    اصل مقاله (655.8 K)
نوع مقاله: Research article
شناسه دیجیتال (DOI): 10.30495/ijbbe.2023.699380
نویسندگان
Bahareh Khaksar Jalali* 1؛ Somayeh Salmani Shik2؛ Latifeh Karimzadeh Bardee3؛ sharifeh shahi4
11. Department of physics, Kharazmi University, Tehran, Iran. 2. Laser and Biophotonics in Biotechnologies Research Center, Islamic Azad University of Isfahan (Khorasgan) branch, Isfahan, Iran.
21. Department of physics, Kharazmi University, Tehran, Iran. 2. Applied Sciences Research Center, Kharazmi University, Karaj, Iran.
3Department of animal biology, Faculty of biological sciences, kharazmi university, Tehran, Iran.
41. Department of Biomedical Engineering, Islamic Azad University of Isfahan (Khorasgan) branch, Isfahan, Iran. 2. Laser and Biophotonics in Biotechnologies Research Center, Islamic Azad University of Isfahan (Khorasgan) branch, Isfahan, Iran.
چکیده
To demonstrate that the Z-scan technique is a reliable approach for diagnosing normal and cancer cells, the absorption coefficient (α), nonlinear refractive index (n2) of normal (MCF10A) and cancer cell lines (MCF7) were examined. According to our findings of the optical properties of cells, cancer cells shown to have higher linear absorption coefficient than normal cells as well as nonlinear refractive index (n2) of different signs but the same order of (10-7 cm2/W). This method is a quick method for differentiating between normal and cancerous breast cells, making it suitable for use in clinical stages in the future. This is because of the obvious fundamental difference between the optical behavior of normal and cancer cells, as well as the affordability, the potential for reproducibility without compromising sample quality, and the high accuracy.
کلیدواژه‌ها
Cancer Diagnosis؛ Linear Absorption؛ MCF7؛ MCF10A؛ Optical Coefficients؛ Z-scan Technique
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