Synthesis of iminofurane derivatives using one pot multicomponent reaction: Dynamic NMR Study

Iranian Journal of Organic Chemistry

دوره 15، شماره 1 - شماره پیاپی 57، اردیبهشت 2023، صفحه 3533-3537   

نوع مقاله: Original Article

شناسه دیجیتال (DOI): 10.30495/iranjoc.2023.699825

نویسندگان

Sayyed Jalal Shams-Najafi^* ؛ Maryam Ghazvini؛ Faramarz Rostami-Charati

چکیده

In this research the reaction between alkyl(aryl) isocyanides, dibenzoylacetylene, ninhydrin and ammonium acetate leads to production of highly functionalized inminofuranes. A dynamic NMR effect is observed in the 1H NMR spectra of these compounds as a result of restricted rotation around the single bond linking the indole moiety and the furan system. The free-energy of activation (ΔG#) for this process is 75-83 kJ mol-1.

کلیدواژه‌ها

Dibenzoylacetylene, Ninhydrin, Alkyl(aryl) isocyanides؛ Dynamic NMR, Ammonium acetate