A Simple and one-pot synthesis of imintriazole derivatives under Solvent-free conditions

Iranian Journal of Organic Chemistry

دوره 15، شماره 1 - شماره پیاپی 57، اردیبهشت 2023، صفحه 3539-3542   

نوع مقاله: Original Article

شناسه دیجیتال (DOI): 10.30495/iranjoc.2023.699826

نویسندگان

Narges Ghasemi؛ Parvaneh Firoozi Khanghah^* ؛ Mahboubeh Ghasemian Dazmiri

چکیده

An efficient synthesis of iminetriazole derivatives is described via an one-pot reaction between acid chlorides, 3-amino-2-butanone, primary amines and hydrazonoyl chloride under solvent-free conditions at room temperature in good yields. Also, the antimicrobial activity of some synthesized compounds proved by employing the disk diffusion test on Gram-positive and Gram-negative bacteria. This procedure has some benefits such as short reaction time, product with excellent yields, simple catalyst and products separation.

کلیدواژه‌ها

Acid chlorides؛ Hydrazonoyl chloride؛ 3-amino-2-butanone؛ Solvent-free؛ One-pot reaction