Antimicrobial and radical scavenging potentials of Euphorbia serpens Kunth

International Journal of Molecular and Clinical Microbiology

دوره 13، شماره 1، اردیبهشت 2023، صفحه 1795-1801   

نوع مقاله: Research Article

شناسه دیجیتال (DOI): 10.22034/ijmcm.2023.700451

نویسندگان

Hamid Beyzaei^{* 1}؛ Mehdi Dehghani²؛ Zahra Ebrahimnezhad²

¹Department of Chemistry, Faculty of Science, University of Zabol, Zabol, Iran

²Department of Biology, Faculty of Science, University of Zabol, Zabol, Iran

چکیده

Euphorbia serpens (Euphorbiaceae) is an annual species native to South America and widely distributed as a weed in pantropical regions. It has attracted attention from academic researchers due to its diverse pharmacological properties. In this study, in vitro antioxidant capacity and antimicrobial activity of various extracts of the roots, and shoots of Euphorbia serpens were investigated using DPPH free radical scavenging assay and disc diffusion method, respectively. Antibacterial activity was tested on three Gram-positive (Streptococcus pneumoniae, Bacillus subtilis subsp. Spizizenii, and Enterococcus faecalis) and three Gram-negative (Shigella flexneri, Proteus vulgaris, and Salmonella typhi) bacteria. The antifungal effect was also examined on three fungi (Aspergillus fumigatus, Candida albicans, and Fusarium oxysporum). Ethanolic shoots extract showed broad-spectrum antimicrobial effects. The best antioxidant activities were also observed with alcoholic shoot extracts. It is concluded that the shoot of Euphorbia serpens is a rich source of bioactive compounds especially if they were extracted by alcohols. They are efficient candidates to treat oxidative stress-related diseases.

کلیدواژه‌ها

Antibacterial activity؛ Antifungal property؛ Antioxidant capacity؛ Euphorbia serpens؛ Medicinal plants