اخبار و اعلانات

 آمار

تعداد نشریات418
تعداد شماره‌ها10,005
تعداد مقالات83,622
تعداد مشاهده مقاله78,355,692
تعداد دریافت فایل اصل مقاله55,395,809
Zhang, Shoude, Jin, Mao, Liu, Jun, Zhang, Lei, Zhao, Yuan, Xiao, Mang, Zhang, Dan, Zhou, Guojin, Lu, Ying. (1401). Topical medication of Tobramycin drops is more effective than Levofloxacinor drops for bacterial suppurative otitis: a retrospective study. نشریه علمی پژوهشی دانشگاه آزاد اسلامی, 13(2), -. doi: 10.47176/IJIC.13.2.3
Shoude Zhang; Mao Jin; Jun Liu; Lei Zhang; Yuan Zhao; Mang Xiao; Dan Zhang; Guojin Zhou; Ying Lu. "Topical medication of Tobramycin drops is more effective than Levofloxacinor drops for bacterial suppurative otitis: a retrospective study". نشریه علمی پژوهشی دانشگاه آزاد اسلامی, 13, 2, 1401, -. doi: 10.47176/IJIC.13.2.3
Zhang, Shoude, Jin, Mao, Liu, Jun, Zhang, Lei, Zhao, Yuan, Xiao, Mang, Zhang, Dan, Zhou, Guojin, Lu, Ying. (1401). 'Topical medication of Tobramycin drops is more effective than Levofloxacinor drops for bacterial suppurative otitis: a retrospective study', نشریه علمی پژوهشی دانشگاه آزاد اسلامی, 13(2), pp. -. doi: 10.47176/IJIC.13.2.3
Zhang, Shoude, Jin, Mao, Liu, Jun, Zhang, Lei, Zhao, Yuan, Xiao, Mang, Zhang, Dan, Zhou, Guojin, Lu, Ying. Topical medication of Tobramycin drops is more effective than Levofloxacinor drops for bacterial suppurative otitis: a retrospective study. نشریه علمی پژوهشی دانشگاه آزاد اسلامی, 1401; 13(2): -. doi: 10.47176/IJIC.13.2.3

Topical medication of Tobramycin drops is more effective than Levofloxacinor drops for bacterial suppurative otitis: a retrospective study

International Journal of Industrial Chemistry
مقاله 3، دوره 13، شماره 2، شهریور 2022
نوع مقاله: research article
شناسه دیجیتال (DOI): 10.47176/IJIC.13.2.3
نویسندگان
Shoude Zhang1؛ Mao Jin1؛ Jun Liu2؛ Lei Zhang1؛ Yuan Zhao2؛ Mang Xiao1؛ Dan Zhang1؛ Guojin Zhou1؛ Ying Lu* 3
1Department of Otolaryngology/Head and Neck, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou 310016, Zhejiang Province, China
2Department of Otolaryngology/Head and Neck, Aral Hospital, Xinjiang Corps, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Aral 843300, Corps, The Xinjiang Uygur Autonomous Region, China
3Department of Otolaryngology/Head and Neck, the First People’s Hospital of Lin’an District, Hangzhou 311300, Zhejiang Province, China
چکیده
Topical medications of Levofloxacinor drops and Tobramycin drops are common therapies for bacterial suppurative otitis. This study aimed to compare the efficacy of the two treatment methods for this disease by retrospective analysis. Total 289 cases prescribed Levofloxacinor drops (n = 154) or Tobramycin drops (n = 135) in the past five years were respectively selected from two hospitals in Zhejiang Province and Xinjiang Uygur Autonomous Region. The total rate of treatment effectiveness of Tobramycin group is 91.1% while that of Levofloxacinor group is 81.2% (P=0.018). Specifically, in chronic cases, Tobramycin group (84.5%) had higher treatment effectiveness than Levofloxacinor group (65.1%) (P=0.0212). The enrolled cases had lower microbial sensitivity to Levofloxacinor (85.8%) than Tobramycin (92.4%), especially to Staphylococcus aureus (Tobramycin 93.5% versus Levofloxacinor 86.5%). For cases with treatment failure, a second treatment was given. Except for cases with Pseudomonas aeruginosa infection, most cases with Levofloxacin treatment failure could be cured by Tobramycin. Conversely, most cases with Tobramycin treatment failure could not be cured by Levofloxacin. In conclusion, Topical medication of Tobramycin drops might be a better or at least good alternative for the empirical treatment of bacterial suppurative otitis.
کلیدواژه‌ها
topical antibiotics؛ empirical treatment؛ Levofloxacinor؛ Tobtamycin؛ suppurative bacterial otitis
آمار
تعداد مشاهده مقاله: 21


سامانه مدیریت نشریات علمی. قدرت گرفته از سیناوب