Application of Water for Synthesis of Cyclopentadienes via Multi-component Reactions of N-methyl imidazole

Journal of Applied Chemical Research

مقاله 1، دوره 10، شماره 1، فروردین 2016، صفحه 7-11   

نوع مقاله: Research Paper

نویسندگان

Alireza Ahmadi Agh Mashhadi؛ Zinatossadat Hossaini^*

چکیده

A water-accelerated multi-component synthesis of organic target molecules was used as a key method for the preparation of cyclopentadiene derivatives. The three-component condensation reactions of primary amines with alkyl propiolates in the presence of N-methylimidazole in water at room temperature were developed as efficient and clean green synthetic procedures for the high-yielding preparation of 4-oxo-2,5-cyclopentadiene-1,2-dicarboxylate derivatives.

کلیدواژه‌ها

Primary Amines؛ N-methylimidazole؛ Alkyl propiolates؛ Multi-component reaction؛ water